CASE REPORT |
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Year : 2021 | Volume
: 1
| Issue : 2 | Page : 99-101 |
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Treatment of highly fatal extensive childhood mucormycosis with complications: A success story
Aakash Chandran Chidambaram1, Jaikumar Govindaswamy Ramamoorthy1, Reena Gulati1, Bhawana A Badhe2
1 Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India 2 Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India
Correspondence Address:
Dr. Reena Gulati Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry - 605 006 India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/ipcares.ipcares_50_21
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Background: Mucormycosis is a highly fatal infection that affects immunocompromised individuals. Treatment is difficult and mortality is high when associated with complications. It is rare as a presenting feature of diabetes mellitus (DM) in children. Clinical Description: We describe a child who presented with extensive rhino-orbital invasive mucormycosis and subsequently diagnosed as Type 1 DM. She further developed cavernous sinus thrombosis and internal carotid artery thrombosis known to be associated with very high risk of mortality. Management: Aggressive medical management with posaconazole and liposomal amphotericin B for 12 weeks and early debridement of orbito-cerebral lesions led to complete resolution. Conclusion: Saving children with complicated extensive invasive mucormycosis is possible with aggressive prolonged antifungal therapy and early debridement of lesions. |
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